Efficient controlled release systems are fundamental for efficient
therapeutical methodologies mainly to improve drug treatment through rate and
time programmed drug delivery. However, the occurrence of multi components instead
of single drug diffusion may complicate the ex- perimental procedure to produce
adequate drug delivery systems. Therefore, mathematical models of controlled
delivery systems are important to simulate the device properties such as the
geometries and physicochemical properties of the system.
This work presents an alternative methodology, based on artificial neural networks
to study drug delivery systems. A drug model system of hydrocortisone was selected
to test the present approach but introducing modifications to increase complexity.
The results of the neural network obtained after the learning stage can be considered
quantitative to predict an ideal experimental condition. The analysis of the
outcome results has shown that one can predict properties of an efficient experiment
with a relative average error smaller than 2%.
*Work supported by CAPES, FAPEMIG and CNPQ, Brazil.